CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial
نویسندگان
چکیده
منابع مشابه
CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial.
OBJECTIVE C-C chemokine receptor type 5 (CCR5), a chemokine receptor expressed on T cells and macrophages, and its ligands are found in inflamed synovial tissue (ST) of patients with rheumatoid arthritis (RA). The rationale for testing CCR5 blockade in patients with RA was supported by the effects of a CCR5 antagonist in collagen-induced arthritis in rhesus monkeys. The effects of CCR5 blockade...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2010
ISSN: 0003-4967,1468-2060
DOI: 10.1136/ard.2010.131235